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89th Faculty Research Lecture
Finding New Genes, Determining Their Functions,
and Watching Their Expression in Living Individuals
Harvey R. Herschman, Ph.D.
Crump Professor of Molecular Imaging , Departments of Biological
Chemistry and Pharmacology
Wednesday,
November 29, 2000
3:00 - 4:30 PM PST |
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Professor Herschman
is a leading figure on fundamental questions of cell growth
and division and its relationship to the development of tumors.
When he came to UCLA in 1969, he became a leading proponent
of the then new technique of cell culture to study these questions. |
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His early studies of the effects of growth factors
on cultured cells evolved into a gene discovery program, focusing
on genes that show a rapid response to a growth stimulus provided
by, for example, a tumor promoter. Among the "early response"
genes that he discovered was a novel prostaglandin cyclooxygenase
gene, subsequently adopted by the pharmaceutical industry for
development of a major drug.
Most recently Dr. Herschman set out to develop a technique that
would permit non-invasive and repetitive tracking of genes introduced
into animals (and eventually into people, in the course of somatic
gene therapy). In close collaboration with the distinguished
positron emission tomography (PET) group at UCLA, he succeeded
in devising such a gene imaging technology. Thus his basic studies
of biochemistry, molecular and cell biology have expanded into
areas of pharmacology and molecular medicine. |
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This event is part of an ongoing series of live events and lectures
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